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Auteur (up) Nemoz-Bertolet, F.; Aujard, F. openurl 
  Titre Physical activity and balance performance as a function of age in a prosimian primate (Microcebus murinus) Type Article scientifique
  Année 2003 Publication Experimental Gerontology Revue Abrégée  
  Volume 38 Numéro 4 Pages 407-414  
  Résumé Physical activity and balance performance were examined in gray mouse lemurs (Microcebus murinus) aging from 1 to 10 years of age. Home cage spontaneous activity, physical and behavioral activities in an open-field test and balance performance at the Rotarod test were evaluated. In this prosimian primate, which life span reaches 8-10 years in captivity, balance performance at the Rotarod test showed a clear decease with age. Latency to fall decreased from 154.7 +/- 13.5 s in the youngest group of animals to 31.2 +/- 5.4 s in animals aging 6 years or more. A significant decrease was noticeable as early as 4 years of age. In a familiar cage, locomotor activity and jumping frequency were reduced in aged animals compared to adults. In contrast, when introduced in an open field, aged animals exhibited an increase in locomotor activity and sniffing frequency when compared to younger animals, while latency to first movement was higher in the adult than in the aged subjects. Based on these results, repeated behavioral testing should be initiated early in the life of this species, in association with an evaluation of visual and olfactory capacities. These findings are important to take into account if detailed evaluations of sensory-motor performances are required in studies on aging processes in primates. (C) 2002 Elsevier Science Inc. All rights reserved.  
  Auteur institutionnel Thèse  
  Editeur Lieu de Publication Éditeur  
  Langue Langue du Résumé Titre Original  
  Éditeur de collection Titre de collection Titre de collection Abrégé  
  Volume de collection Numéro de collection Edition  
  ISSN 0531-5565 ISBN Médium  
  Région Expédition Conférence  
  Notes WOS:000182556200008 Approuvé pas de  
  Numéro d'Appel MNHN-CNRS @ hackert @ collection 77  
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